Effect of St. John's wort + Bupron (Bupropion SR) - 150 mg

Due to the tiredness I felt after taking St. John's wort for 1 month, I thought of adding bupropion SR 150 mg.  I  took the combination only on one day.


Positive effects:

• Slightly improved energy
• A long pause before starting the speech which made me embarrassed in the meeting. subsequently it led me to sink in negative thoughts.

Negative effects:

• Low mood in the evening
• Depressive thoughts and thoughts about death ("death is the only solution")

With single dose, no conclusion can derived. The combination can be tried for few more days.