Effect of St. John's Wort

For the last 1 month I took St. John's wort 300 mg, (Kordel’s St. John's Wort 300mg), standardized to contain 0.3% of hypericin.

 

Positive effects:

• No Depressive negative thoughts
• Reduced anxiety - but this reduction is lesser than that experienced with bupropion.
• Slightly strong erections
• Stuttering was mild and I could overcome that
• Not much of sleepiness. Reduced hypersomnia.

Negative effects:

• Pronounced tiredness
• Lack of focus and concentration
• Lack of motivation - unable to initiate work

Interpretation:

• Pronounced GABA agonism effect which might have subsequently decreased dopamine
• Less agonism effect on serotonergic system.