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Showing posts with label Vitamin C. Show all posts
Showing posts with label Vitamin C. Show all posts

Tuesday, December 15, 2020

Easy ways to increase penile erection in man with erectile dysfunction (ED)

I have followed the following ways to increase the erection function. Please read the basic physiology/pathology of erection and erectile dysfunction so as to have a better understanding and better cure of your condition.

The penile erection in males is largely governed by vascular health because the erection and flaccidity of penis is dependent upon blood flow and trapping of that blood inside the spongy penile tissue. The blood vessels should have appropriate elasticity to do this job. This elasticity is mediated by several mechanisms. Among them, nitric oxide (Chemical formula: NO) is important in mediating penile erection. This nitric oxide molecule is generated by the blood vessel (vascular endothelium) itself. Therefore, bad vascular condition will impair the synthesis of nitric oxide. Furthermore, nitric oxide is short-lived (decompose in few seconds). Antioxidant (endogenous and exogenous) molecules protect nitric oxide from decomposing quickly. Therefore, decreased levels of antioxidants in the body will cause less availability of nitric oxide subsequently leading to erectile dysfunction.

So, what causes decrease of antioxidants in body?

The core answer is inflammation and other related processes will lead to the decrease of antioxidant defense in the body.

Oh.. What causes inflammation in body?

Several chronic diseases/disorders cause inflammation and related processes to rise in the body such as diabetes, cardiovascular diseases, hyperlipidemia, and psychological stress disorders such as anxiety, depression etc. Even in people without these disorders, many young persons have metabolic syndrome. Metabolic syndrome also has inflammatory component in it. Many appear-to be healthy people have insulin resistance. Insulin increases nitric oxide production. So, insulin resistance (cells resist the normal levels of insulin; so higher levels of insulin are required to transport glucose into cells and transport amino acids into skeletal muscle cells). Insulin resistance appears to be a starting point in many people who develop erectile dysfunction as insulin resistance seems to be starting problem for diabetes and cardiovascular disorders. Insulin resistance appears to linked with inflammation.

Then, how to reduce inflammation and decrease insulin resistance?

No perfect medicine is available as of now. Various lifestyle modifications and supplements are recommended to decrease inflammation and insulin resistance. Exercise is the best in this category. Moderate aerobic exercise and weight training are recommended. Avoid heavy and strenuous exercises as it will increase oxidative stress and inflammation.

What should I eat/avoid?

a. Avoid refined sugar, white bread/white rice - these foods increase oxidative stress in body

b. Avoid high fat food - these foods increase oxidative stress in body

c. Eat low low glycemic foods and low-insulinemic foods.

d. Do fasting for at least 12 hours a day. Practice this regularly or in weekends. Consume all your food within 12 hours window and fast during the remaining 12 hours of a day. You can take water. But, strictly no calories.

c. Eat more antioxidants/take supplements

Hmm...I am already following one or more of the above recommendations. What supplements can I take further?

1. Consumption of vitamin C

I have taken 250 mg - 500 mg vitamin C daily 2-3 times after the food. It increases body heat and erection. If this works for you, probably you can assume that you have insulin resistance and inflammation in your body.

2. Folic acid

I have taken 1 mg - 3 mg of folic acid one time daily. This increases my mood and when combined with vitamin C gave better erections.

3. Multivitamin tablets/capsules

I usually take a multivitamin tablet/capsule everyday as it helps to reduce the inflammation and improve the general well-being feeling. Multivitamin with ginseng worked for me earlier. Nowadays, it is not working.

4. DL-phenylalanine

250 mg-500 mg of DL-phenylalanine increased the erections.


Reference:

Lifestyle and metabolic approaches to maximizing erectileand vascular health. International Journal of Impotence Research (2012) 24, 61–68.


Disclaimer: This is not a medical advice and I am not a medical doctor. The above statements are not authorized/validated/approved by any drug approving authority. Please do not take any supplement/medicine on your own. Please consult a doctor for your illness. 


Saturday, July 25, 2020

Hoarse voice, Sore throat, Vitamin C and Electrolytes

I usually get hoarse voice and/OR sore throat if i talk for few hours at a stretch or if i lecture with loud volume for 1 hour. This could be due to easy bruising of throat muscles and vocal cards and less hydration of throat muscles and vocal cards.

The possible solutions/treatments to these problems can be as follows:

1. Take vitamin C
2. Stay hydrated - Take electrolyte solutions before lecture

Update on 20 Sep 2020:
Folic acid may be helpful. Please see the effect of folic acid in another post.

Saturday, January 15, 2011

My finalized treatment plan II

When I was taking pharmaton capsules with ginseng and selenium, my libido was boosted up, my mood was up, my motivation level was OK but my stuttering and loudness of voice were worsened with time. I experienced non stutterable pause in my speech and inrregular breathing while speaking. This irregular breathing led to unfinished words and incomplete sentences (where I spoke words that did not have enough volume to be heard by the other person. It occured at the end of the speech). I feel that these effects could be due to the accumulation of trace minerals in the body. I learnt from one article published in jorunal of orthomolecular medicine that minerals and vitamins do have agonism and antagonism effect with other minerals and vitamins. Copper regulates GABA and dopamine neurotransmission. So, when I was taking pharmaton capsules with selenium and ginseng (contains copper 2 mg), it might have affected my GABA and dopamine neurotransmission. And also, it contains only 1 mg of zinc. So, i feel these two factors along with selenium (50 mcg) were responsible for the observed side effects.

 
Hence, I decided to try a formulation without much of these trace minerals. Because, I feel that trace minerals when supplemented to 100% of RDA, they may accumulate in the body and produce toxic symptoms. So, I tried Blackmores Executive B tablets. I am doing stationary bicycling for 30 minutes in the morning also. I am using lifebuoy's mild care body wash for bathing and no deodorant and no body sprays.

Positive effects:
  • Good and pleasant mood - no worries and no fears
  • Reduced anxiety while speaking and driving
  • Reduced stuttering - improved fluency and improved loudness and no pronounced non stutterable pause. A slight pause or delay occurs sometimes but I could overcome it by pronouncing other substituted words.
  • Able to complete the long sentences with the same volume.
  • More bass frequency in the voice - bass frequency increases with noodle intake probably with wheat intake.
  • Good affection towards wife - led to no arguments and no fights with wife
  • Slightly improved libido - however libido is lesser than that obtained with pharmaton capsules with selenium and ginseng. I have observed that while taking these combination, the libido increases proportionately with increase in protein intake in the lunch or in the breakfast.
  • Erections are strong. 
  • Motivation is good enough for me to sustain in the failing research work instaed of escaping.
  • Concentration is also good enough to sustain in the tasks until complete. But, after taking lunch, tiredness occurs and concentration drops.

Negative effects:
  • Tiredness after taking lunch.
  • Feeling sleepy after taking lunch despite taking tea.
  • Loudness of voice is not as much as when obtained with 5-HTP and DL-Phenylalanine.
  • Even though alertness is there while driving, reduced anxiety makes me to think other things other than driving. This effect may also be due to adaptation for driving. 

Suggestions:
  • To improve the libido, ginseng can be added 20-40 mg of ginseng extract standardised to 4% ginsenosides.
  • To improve the loudness of voice, DL-phenylalanine can be added in the morning OR folic acid 800 mcg may be tried in the morning OR 400 mcg of folic acid in morning and 400 mcg of folic acid in lunch may be tried.


 
Composition of Blackmores executive B tablets:
 
Vitamin C (Ascorbic acid)180 mg
Vitamin B3 (Nicotinamide)60 mg
Vitamin B6 (Pyridoxine hydrochloride)10 mg
Vitamin B2 (Riboflavin)8.5 mg
Vitamin B1 (Thiamine nitrate)7.5 mg
Biotin50 mcg
Vitamin B5 (Pantothenic acid)
20 mg
Folic acid200 mcg
Potassium (from Potassium sulfate)75 mg
Magnesium (from Magnesium phosphate)175 mg
Vitamin B12 (Cyanocobalamin)10 mcg
Zinc (from Zinc sulfate)15 mg
 
In this formulation zinc is present as almost 100% of RDA and magnesium as ~50% of RDA. Along with this formulation I am taking folic acid 400 microgram also in the morning.

 
Time and foodDrugsRemarks
Morning - Breakfast with low fat noodles or rice noodles - 1 packet ~ 250kcal

Blackmores Executive B multivitamin tablet - 1


Folic acid - 400 microgram - 1 tablet
This multivitamin formulation contains anti-stress vitamins and minerals. Executive B contains 200 microgram of folic acid. But, I feel that I may need more folic acid since my homocysteine level is on the borderline high. So I take 400 microgram of folic acid. This gives me more energy, good mood, good loudness in voice (loudness is not as louder when supplemented with 5-HTP and DL-phenylalanine), less stuttering and less anxiety. 
Noon - Lunch with rice, Indian curry (avoid protein intake)No drugsProtein intake is avoided to minimize the fluctuations in neurotransmitter levels mainly to avoid stuttering. Protein intake in the morning or in the lunch increases adrenaline, noradrenaline and dopamine and give more energy but at the same time producing more pronounced stuttering. So, protein intake can be safely allocated to the night meal. Then the next whole day's neurotransmitter levels can be maintained adequately.
Night - Dinner with rice or bread or chappathi or low fat noodles or rice noodles with one piece of fried chicken preferably with a chicken breast piece
 

 

 

 

No drugs
 

 

 

 
  Once I took 400 mcg of folic acid. It produced tiredness next day probably interfering with sleep cycles. Once I took omega 3 supplement in night, it made me tired next day and made me to sleep excessively.