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Wednesday, August 17, 2011

Effect of fluoxetine and supradyn recharge

Although I could achieve better results with the previous treatment plans I and II, still I had stuttering while talking on phone and to strangers. Sometimes the telephonic conversation occupy vital part of talking (like transaction negotiation or making an appointment) and stuttering at those timings gave me very worst embarassing.

So, I wanted to try fluoxetine again.

I took fluoxetine 20 mg once daily in the morning along with executive B multivitamin tablets. This combination gave me the following.

Positive effects:
  • Moderate energy and motivation
  • No effect on sexual function (good erections and good libido)
  • Less stress, anxiety and depression
Negative effects:
  • More pronounced stuttering.
  • Heavily sleepy during day time especially after lunch.
  • Heavy and profuse sweating.
Mechanism explanation:
  • The Executive B multivitamin contains pyridoxine (Vit. B6) 10 mg. This amount might have catalysed the synthesis of huge quantity of serotonin.
  • Increased serotonin synthesis might have led to increased 5-HT neurotransmission and subsequently increased dopamine neurotransmission in the speech area of brain thus producing more stuttering. 
So, I decided to reduce the amount of Vit. B6. Supradyn recharge naturally came as a first choice since it contained 5 mg of Vit. B6. So, I took fluoxetine 20 mg and supradyn recharge 1 capsule in the morning after breakfast. It produced less stuttering in the evening and more sleepiness and stuttering in the morning. Then I decided to change the timing of these two drugs. I took fluoxetine in the night after dinner and supradyn recharge capsules in the morning after breakfast. This combination produced wonderful effects on my stuttering.

Positive effects:
  • Almost no stuttering and very clear speech except for the rare occurrence of mispelt words.
  • Good loudness of voice without gasping for breath.
  • Greater reduction of anxiety
  • No feelings of depression - no negative feelings and worrying
  • Very good judgement of space while driving car.
  • Very good memory recall of routes while driving.
  • Good sense of well being
  • Almost no effect of food on stuttering - earlier if i consume protein in the lunch, my stuttering used to be worse. Now, whatever food I consmed did not affect my stuttering. So, I removed restrictions on my food type.
  • Good sleep in the night.
  • Good self control.
  • Good control of blood pressure - 128/87 mm Hg with 86 pulse rate.
Negative effects:
  • Motivation to start and remain in a task is reduced significantly
  • Concentration to sustain in a task is also reduced significantly.
  • Libido is also reduced significantly. But erections used to be slow onset and not much of a problem. Orgasm was delayed or did not occur in some instances. Libido was increased if supradyn recharge was not taken in the morning.
  • Heavy and profuse sweating.
  • Music is not enjoyable as before.
Suggestions:
  • Either Vitamin C or DL-phenylalanine may be added in the morning or in the lunch time to increase concentration and motivation. However, care should be taken not to disturb the achieved fluency levels.  

Tuesday, June 28, 2011

Composition of Supradyn Recharge Multivitamin Capsules (Bayer)


Each capsule contains

Quantity
% US RDA
12 Vitamins


Vitamin A (1 mg)
3333 I.U.
100
Vitamin B1
4.5 mg
300
Vitamin B2
5.1 mg
300
Vitamin B6
6 mg
300
Vitamin B12
6 mcg
300
Vitamin C
180 mg
300
Vitamin D3 (3 mcg)
200 I.U.
100
Vitamin E
10 mg
100
Biotin
0.3 mg
100
Pantothenic acid
21 mg
200
Folic acid
0.2 mg
100
Nicotinamide
57 mg
350
8 Minerals and trace elements
Calcium
50 mg
5
Magnesium
40 mg
10
Phosphorus
50 mg
5
Chromium
10 mcg
8
Copper
0.4 mg
20
Iron
3.6 mg
36
Manganese
0.5 mg
14
Zinc
3 mg
20

Composition of Centrum multivitamin tablets


Centrum® Tablets

Supplement Facts


Serving Size 1 Tablet



Each Tablet Contains
% Daily Value



Vitamin A 3500 IU (29% as Beta-Carotene)
70%


Vitamin C 60 mg
100%


Vitamin D 400 IU
100%


Vitamin E 30 IU
100%


Vitamin K 25 mcg
31%


Thiamin 1.5 mg
100%


Riboflavin 1.7 mg
100%


Niacin 20 mg
100%


Vitamin B6 2 mg
100%


Folic Acid 400 mcg
100%


Vitamin B12 6 mcg
100%


Biotin 30 mcg
10%


Pantothenic Acid 10 mg
100%


Calcium 200 mg
20%


Iron 18 mg
100%


Phosphorus 20 mg
2%


Iodine 150 mcg
100%


Magnesium 50 mg
13%


Zinc 11 mg
73%


Selenium 55 mcg
79%


Copper 0.5 mg
25%


Manganese 2.3 mg
115%


Chromium 35 mcg
29%


Molybdenum 45 mcg
60%


Chloride 72 mg
2%


Potassium 80 mg
2%



Boron 75 mcg
*


Nickel 5 mcg
*


Silicon 2 mg
*


Tin 10 mcg
*


Vanadium 10 mcg
*



* Daily Value not established.



Source: http://www.centrum.com/productdetail.aspx?BrandProductId=40