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Wednesday, May 20, 2015

Effect of Turmeric

I was taking turmeric powder since the scientific literature indicated that it can increase testosterone and inhibit aromatase enzyme. I took it for around 1 week. I took around 500 mg to 1 g of turmeric powder mixed with dosa flour or mixed with egg omlette. I took one time in the morning sometimes and both in morning and dinner sometimes.

Positive effects:
1. Generally good mood
2. Slightly increased focus and concentration
3. Slightly reduced stuttering
4. Early morning erections are rock solid
5. Slightly improved libido and motivation

Negative effects:
1. Increased sweating
2. Slightly increased agitated mood
3. Tightness in the chest - this effect was very significant and caused great discomfort to me. The chest muscles seem to be not relaxing and contracting like before. The chest tightness combined with muscle pain in hand caused great distress.
4. When I took turmeric two times a day (at breakfast and dinner), it caused severe left sided headache (serotonin deficiency). The headache persisted for almost two days. It did not subside after taking 650 mg paracetamol. It went away only after I stopped taking turmeric.

Possible mechanism:
Turmeric might have increased cortisol. This increased cortisol might have caused decreased serotonin. The exact mechanism needs to be studied further.

Turmeric compounds might have increased acetylcholine levels by inhibiting acetylcholinesterase enzyme and activating choline acetyl transferase enzyme.

References:
Combined administration of curcumin and gallic acid inhibits gallic acid-induced suppression of steroidogenesis, sperm output, antioxidant defenses and inflammatory responsive genes.

Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease

Update on 18 Feb 2018:

I used to develop the same chest pain (exactly the pain the sternum and adjacent rib muscles). It does not pain normally. It pains sometimes whenever I turn my body and whenever I press the sternum ribs. Otherwise, it doesn't give any pain during walking or climbing stairs or even during exercise in elliptical trainer.

Recently also, I cooked a curry with some turmeric in it. After two times consumption of that curry, I got that pain again. Now, I am taking the following supplements:

Blackmore Multivitamin + Minerals - 1 tablet in morning
Thiamine mononitrate - 25 mg in morning and 25 mg in night
Blackmore Vitamin D3 - 1000 mcg - 1 capsule in morning
L-Tryptophan 500 mg - 1 capsule in night

Also, I consumed 2-3 eggs (enriched with organic selenium) per day. No other non-vegetarian food was consumed during these days. Within two days, the pain subsided. Is it due to selenium or tryptophan?




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