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Sunday, April 24, 2016

Natural dopamine antagonists and stuttering

Excessive dopamine in the brain appears to be the causative factor for stuttering in me. As of now, I do not know which part of my brain has excessive dopamine. It may not be really excessive, but may be a relative high level of dopamine compared to other antagonistic neurotransmitters such as serotonin, GABA and acetyl choline in specific parts of the brain which are involved in speech production. Hence, either decreasing dopamine or increasing serotonin, GABA and acetylcholine in those specific parts of the brain may be beneficial in reducing stuttering and achieving fluency. However, as of now, it is not clear exactly in which parts of the brain of stutterers, dopamine is relatively excessive.

In my experimentation with various supplements and drugs, I have observed that the following supplements increase dopamine and worsen stuttering and other issues of speech dis fluency in me. I tried to put them in the order of their effect (descending order). The first supplement causes more stuttering than the second supplement.

Supplements that increase dopamine and increase/worsen stuttering:

1. Omega-3 fatty acids (fish oil) above 100 mg per day
2. Ginkgo biloba
3. Zinc above 6 mg per day
4. Ginseng
5. Vitamin B6 above 6 mg per day
6. Coffee


Supplements that decrease dopamine and reduce stuttering: I tried to put them in the order of their effect (descending order). The first supplement causes maximum reduction of stuttering than the second supplement.

1. Ashwagandha (250 mg extract two times a day; one in morning and one in evening; can feel the effect after 2-3 doses; but it decreases serotonin also; hence, I get negative thoughts)
2. Vitamin C instant release above 250 mg per dose (100 mg taken at night gives better effect next morning)
3. Butter (taken at night gives better effect next morning)