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Wednesday, August 17, 2011

Effect of fluoxetine and supradyn recharge

Although I could achieve better results with the previous treatment plans I and II, still I had stuttering while talking on phone and to strangers. Sometimes the telephonic conversation occupy vital part of talking (like transaction negotiation or making an appointment) and stuttering at those timings gave me very worst embarassing.

So, I wanted to try fluoxetine again.

I took fluoxetine 20 mg once daily in the morning along with executive B multivitamin tablets. This combination gave me the following.

Positive effects:
  • Moderate energy and motivation
  • No effect on sexual function (good erections and good libido)
  • Less stress, anxiety and depression
Negative effects:
  • More pronounced stuttering.
  • Heavily sleepy during day time especially after lunch.
  • Heavy and profuse sweating.
Mechanism explanation:
  • The Executive B multivitamin contains pyridoxine (Vit. B6) 10 mg. This amount might have catalysed the synthesis of huge quantity of serotonin.
  • Increased serotonin synthesis might have led to increased 5-HT neurotransmission and subsequently increased dopamine neurotransmission in the speech area of brain thus producing more stuttering. 
So, I decided to reduce the amount of Vit. B6. Supradyn recharge naturally came as a first choice since it contained 5 mg of Vit. B6. So, I took fluoxetine 20 mg and supradyn recharge 1 capsule in the morning after breakfast. It produced less stuttering in the evening and more sleepiness and stuttering in the morning. Then I decided to change the timing of these two drugs. I took fluoxetine in the night after dinner and supradyn recharge capsules in the morning after breakfast. This combination produced wonderful effects on my stuttering.

Positive effects:
  • Almost no stuttering and very clear speech except for the rare occurrence of mispelt words.
  • Good loudness of voice without gasping for breath.
  • Greater reduction of anxiety
  • No feelings of depression - no negative feelings and worrying
  • Very good judgement of space while driving car.
  • Very good memory recall of routes while driving.
  • Good sense of well being
  • Almost no effect of food on stuttering - earlier if i consume protein in the lunch, my stuttering used to be worse. Now, whatever food I consmed did not affect my stuttering. So, I removed restrictions on my food type.
  • Good sleep in the night.
  • Good self control.
  • Good control of blood pressure - 128/87 mm Hg with 86 pulse rate.
Negative effects:
  • Motivation to start and remain in a task is reduced significantly
  • Concentration to sustain in a task is also reduced significantly.
  • Libido is also reduced significantly. But erections used to be slow onset and not much of a problem. Orgasm was delayed or did not occur in some instances. Libido was increased if supradyn recharge was not taken in the morning.
  • Heavy and profuse sweating.
  • Music is not enjoyable as before.
Suggestions:
  • Either Vitamin C or DL-phenylalanine may be added in the morning or in the lunch time to increase concentration and motivation. However, care should be taken not to disturb the achieved fluency levels.